CRYO-S Painless for cryoanalgesia in pain management


CRYO-S ® Painless

Steps to the painless future

Most technologically advanced device for cryoneurolisis.

Mode selection probe, cleaning and freezing can be performed automatically using footswitch or convenient touch screen which allows to keep the site of a procedure under sterile conditions.

RFiD – electronic communication between the probe and device allows recognition of optimal operating parameters and auto-configures to cryoprobe characteristic. Pressure and gas flow are set automatically, any manual adjustment is not necessary.

Contains automatic cryoprobe test system and two freezing modes (continous and sequential). Probe test system includes autocleaning and short freezing test.

Built-in voice communication for easier work. System informing about key figures during procedure.

Diagnostic nervestimulation built-in helps to distinguish between sensory and motor nerves. It prevents from accidental freezing of motor nerves.

The working medium for CRYO-S ®  Painless is carbon dioxide: CO2 (-78°C) or nitrous oxide: N2O (-89°C), very efficient and easy to use gases. A 10 liter cylinder of CO2/N2O serves for approximately 60 procedures.

User friendly interface

CRYO-S ® Painless is controlled by a microprocessor and all the parameters are displayed and monitored on a LCD screen. Cryoprobe temperature, cylinder pressure, gas flow inside of cryobrobe and procedure time are displayed during freezing.

Cryoanalgesia – release from chronic pain

For the patients with chronic pain at the level of over 5 in visual analogue scale (VAS).

The advantages of Cryoanalgesia

  • No more “pain killers”
  • Immediate pain reduction
  • No neuroma formation – no risk of secondary pain
  • High efficiency: pain reduction from 6 months to 2 years
  • Can be repeated – nerve grows back
  • Simple diagnostics: fluoroscopy or echography
  • No scar tissue formation
  • Suitable for patients with pacemakers and stimulators
  • No risk of vessel proliferation and obliteration
  • Fast return to normal activity – no hospitalization

Clinical application

  • Knee pain prior or secondary to infrapatellar branch of the saphenous nerve, anterior femoral cutaneous nerve, genicular nerve after knee arthroplasty or total knee replacement
  • Various types of peripheral neuropathy
  • Diabetic neuropathy
  • Low back pain and lower extremity pain secondary to lumbar facet joint pathology, pseudosciatica
  • Phantom pain
  • Morton’s neuroma, heel pain
  • Sacroiliac joint pain, cluneal neuralgia, obturator neuritis
  • Chest wall pain with multiple conditions including post-thoracotomy neuromas, persistent pain after rib fractures and post herpetic neuralgia in thoracic distribution
  • Abdominal and pelvic pain secondary to ilioinguinal, iliohypogastric, genitofemoral, subgastric neuralgia, pudendal neuralgia
  • Craniofacial pain secondary to trigeminal neuralgia, posterior auricular neuralgia, and glossopharyngeal neuralgia
  • Upper extremity pain secondary to suprascapular neuritis and other conditions of peripheral neuritis

30 years of experience

       CRYO-S ® PAINLESS state-of-the-art cryosurgical device manufactured by METRUM CRYOFLEX is the next generation of apparatus used by many experts in the field since 1992.

The best cryoprobes ever

The thinnest cryoprobes for cryoanalgesia available on the global pain management market. We are offering both single use and multiple use, easy to sterilize (steam) cryoprobess. The special construction enables precise freezing and fast defrosting.

Cryoprobes are all covered with medical teflon. That is why the stimulation is possible only at the probe tip.

All cryprobes are visible in the ultrasound images- they are hyperechogenic.

The largest range of cryobrobes alows to find the best solution.

Single-use cryoprobe


1.3 mm, lesion up to 15 mm


0.8 mm, lesion up to 6 mm


1.3 mm, lesion up to 10 mm

Sacroiliacjoint cryoprobe


2 mm, lesion up to 40 mm

No more painkillers

        Cryoanalgesia is a minimally invasive and safe procedure recommended especially when traditional methods prove to be unsatisfactory.

How it works?


  • Power requirements
    • Power 100÷240 V (50/60 Hz) AC
    • Maximum power consumption 150 VA
  • Cooling medium
    • CO2- 78°C or N2O – 89°C
    • Maximum pressure 70 bars (CO2) and 55 bars (N2O)
    • Working pressure 48÷65 bars (CO2), 38-53 bars (N2O)
  • LCD screen (touch)
  • Voice information system (information about key figures during procedure)
  • Comfortable foot switch controller (dual function)
  • Automatic/Manual control of the flow rate parameters
  • Automatic gas pressure control
  • Freezing temperature control
  • Two operation modes (auto and manual)°
  • Built-in neurostimulator with 2 types of stimulation (sensory and motor) and variety of options for manual settings
    • for motor stimulation: 1 and 2 Hz
    • for sensory stimulation: 50, 100, 150, 200 Hz
    • Impulse width setting: 0.1, 0.2, 0.5, 1.0, 2.0-5.0 ms
Functional modes of unique cryoprobe prepairing system:
  • Standard – cryoprobe is automatically purged before each procedure for several seconds and then a few seconds of testing freezing is performed. In this mode cryoprobe is tested and prepared according to parameters programmed on attached microchip. When such preparation is finished cryoprobe is ready for freezing.
  • Service – it starts automatically when decreased flow rate in cryoprobe or cryoprobe blockage is noticed. It can be performed also during the procedure. Service mode is diagnosing and solving problems caused by previous improper use of the cryoprobe.
  • Dimensions: 39/42/19 cm

  • Weight: 11 kg

Choose the best solution

CRYO-S ® Painless is used by the gratest specialists in the world.